Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ascl1  achaete-scute family bHLH transcription factor 1   (Synonyms: ASH1, bHLHa46, Mash1)
Results	Reference
1	J:109287 Balmer CW, LaMantia AS, Loss of Gli3 and Shh function disrupts olfactory axon trajectories. J Comp Neurol. 2004 May 3;472(3):292-307
1	J:308131 Blizzard LE, Menke C, Patel SD, Waclaw RR, Lachke SA, Stottmann RW, A Novel Mutation in Cse1l Disrupts Brain and Eye Development with Specific Effects on Pax6 Expression. J Dev Biol. 2021 Jul 7;9(3)
1	J:95822 Cai J, Qi Y, Hu X, Tan M, Liu Z, Zhang J, Li Q, Sander M, Qiu M, Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling. Neuron. 2005 Jan 6;45(1):41-53
1*	J:143541 Chen L, Melendez J, Campbell K, Kuan CY, Zheng Y, Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly. Dev Biol. 2009 Jan 1;325(1):162-70
1	J:126065 Costa MR, Kessaris N, Richardson WD, Gotz M, Hedin-Pereira C, The marginal zone/layer I as a novel niche for neurogenesis and gliogenesis in developing cerebral cortex. J Neurosci. 2007 Oct 17;27(42):11376-88
1	J:336102 Eenjes E, Benthem F, Boerema-de Munck A, Buscop-van Kempen M, Tibboel D, Rottier RJ, Distinct roles for SOX2 and SOX21 in differentiation, distribution and maturation of pulmonary neuroendocrine cells. Cell Mol Life Sci. 2023 Mar 3;80(3):79
1	J:201994 Ehrman LA, Mu X, Waclaw RR, Yoshida Y, Vorhees CV, Klein WH, Campbell K, The LIM homeobox gene Isl1 is required for the correct development of the striatonigral pathway in the mouse. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):E4026-35
1	J:329939 Everlien I, Yen TY, Liu YC, Di Marco B, Vazquez-Marin J, Centanin L, Alfonso J, Monyer H, Diazepam binding inhibitor governs neurogenesis of excitatory and inhibitory neurons during embryonic development via GABA signaling. Neuron. 2022 Oct 5;110(19):3139-3153.e6
1	J:112208 Fotaki V, Yu T, Zaki PA, Mason JO, Price DJ, Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3. J Neurosci. 2006 Sep 6;26(36):9282-92
1	J:304603 Fujita I, Shitamukai A, Kusumoto F, Mase S, Suetsugu T, Omori A, Kato K, Abe T, Shioi G, Konno D, Matsuzaki F, Endfoot regeneration restricts radial glial state and prevents translocation into the outer subventricular zone in early mammalian brain development. Nat Cell Biol. 2020 Jan;22(1):26-37
1	J:127074 Glickstein SB, Moore H, Slowinska B, Racchumi J, Suh M, Chuhma N, Ross ME, Selective cortical interneuron and GABA deficits in cyclin D2-null mice. Development. 2007 Nov;134(22):4083-93
1	J:95357 Gregg C, Weiss S, CNTF/LIF/gp130 receptor complex signaling maintains a VZ precursor differentiation gradient in the developing ventral forebrain. Development. 2005 Feb;132(3):565-78
1	J:188519 Guha A, Vasconcelos M, Cai Y, Yoneda M, Hinds A, Qian J, Li G, Dickel L, Johnson JE, Kimura S, Guo J, McMahon J, McMahon AP, Cardoso WV, Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12592-7
1	J:310880 Han S, Okawa S, Wilkinson GA, Ghazale H, Adnani L, Dixit R, Tavares L, Faisal I, Brooks MJ, Cortay V, Zinyk D, Sivitilli A, Li S, Malik F, Ilnytskyy Y, Angarica VE, Gao J, Chinchalongporn V, Oproescu AM, Vasan L, Touahri Y, David LA, Raharjo E, Kim JW, Wu W, Rahmani W, Chan JA, Kovalchuk I, Attisano L, Kurrasch D, Dehay C, Swaroop A, Castro DS, Biernaskie J, Del Sol A, Schuurmans C, Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding. Neuron. 2021 Sep 15;109(18):2847-2863.e11
1*	J:314664 Harada Y, Yamada M, Imayoshi I, Kageyama R, Suzuki Y, Kuniya T, Furutachi S, Kawaguchi D, Gotoh Y, Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module. Nat Commun. 2021 Nov 12;12(1):6562
1	J:67408 Hartfuss E, Galli R, Heins N, Gotz M, Characterization of CNS precursor subtypes and radial glia. Dev Biol. 2001 Jan 1;229(1):15-30
1	J:75661 Heins N, Malatesta P, Cecconi F, Nakafuku M, Tucker KL, Hack MA, Chapouton P, Barde YA, Gotz M, Glial cells generate neurons: the role of the transcription factor Pax6. Nat Neurosci. 2002 Apr;5(4):308-15
1	J:176838 Holowacz T, Huelsken J, Dufort D, van der Kooy D, Neural stem cells are increased after loss of beta-catenin, but neural progenitors undergo cell death. Eur J Neurosci. 2011 Apr;33(8):1366-75
1	J:64088 Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H, Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000 Sep;127(18):3913-21
1	J:116627 Kameda Y, Nishimaki T, Miura M, Jiang SX, Guillemot F, Mash1 regulates the development of C cells in mouse thyroid glands. Dev Dyn. 2007 Jan;236(1):262-70
1	J:266224 Kelenis DP, Hart E, Edwards-Fligner M, Johnson JE, Vue TY, ASCL1 regulates proliferation of NG2-glia in the embryonic and adult spinal cord. Glia. 2018 Sep;66(9):1862-1880
1	J:204046 Li Y, Linnoila RI, Multidirectional differentiation of Achaete-Scute homologue-1-defined progenitors in lung development and injury repair. Am J Respir Cell Mol Biol. 2012 Dec;47(6):768-75
1	J:190886 Morimoto M, Nishinakamura R, Saga Y, Kopan R, Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells. Development. 2012 Dec 1;139(23):4365-73
1	J:251094 Neumann JE, Wefers AK, Lambo S, Bianchi E, Bockstaller M, Dorostkar MM, Meister V, Schindler P, Korshunov A, von Hoff K, Nowak J, Warmuth-Metz M, Schneider MR, Renner-Muller I, Merk DJ, Shakarami M, Sharma T, Chavez L, Glass R, Chan JA, Taketo MM, Neumann P, Kool M, Schuller U, A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors. Nat Med. 2017 Oct;23(10):1191-1202
1	J:174732 Pacary E, Heng J, Azzarelli R, Riou P, Castro D, Lebel-Potter M, Parras C, Bell DM, Ridley AJ, Parsons M, Guillemot F, Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron. 2011 Mar 24;69(6):1069-84
1	J:121096 Parras CM, Hunt C, Sugimori M, Nakafuku M, Rowitch D, Guillemot F, The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes. J Neurosci. 2007 Apr 18;27(16):4233-42
1	J:245925 Pfurr S, Chu YH, Bohrer C, Greulich F, Beattie R, Mammadzada K, Hils M, Arnold SJ, Taylor V, Schachtrup K, Uhlenhaut NH, Schachtrup C, The E2A splice variant E47 regulates the differentiation of projection neurons via p57(KIP2) during cortical development. Development. 2017 Nov 01;144(21):3917-3931
1*	J:119877 Quinn JC, Molinek M, Martynoga BS, Zaki PA, Faedo A, Bulfone A, Hevner RF, West JD, Price DJ, Pax6 controls cerebral cortical cell number by regulating exit from the cell cycle and specifies cortical cell identity by a cell autonomous mechanism. Dev Biol. 2007 Feb 1;302(1):50-65
1	J:294332 Romanov RA, Tretiakov EO, Kastriti ME, Zupancic M, Haring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, Clotman F, Andrews WD, Parnavelas JG, Farlik M, Bock C, Adameyko I, Hokfelt T, Keimpema E, Harkany T, Molecular design of hypothalamus development. Nature. 2020 Jun;582(7811):246-252
1	J:171312 Sammeta N, Hardin DL, McClintock TS, Uncx regulates proliferation of neural progenitor cells and neuronal survival in the olfactory epithelium. Mol Cell Neurosci. 2010 Dec;45(4):398-407
1	J:328873 Shang Z, Yang L, Wang Z, Tian Y, Gao Y, Su Z, Guo R, Li W, Liu G, Li X, Yang Z, Li Z, Zhang Z, The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331
1	J:218988 Smith KM, Maragnoli ME, Phull PM, Tran KM, Choubey L, Vaccarino FM, Fgfr1 inactivation in the mouse telencephalon results in impaired maturation of interneurons expressing parvalbumin. PLoS One. 2014;9(8):e103696
1	J:81762 Stenman J, Yu RT, Evans RM, Campbell K, Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon. Development. 2003 Mar;130(6):1113-22
1*	J:294646 Stupnikov MR, Yang Y, Mori M, Lu J, Cardoso WV, Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
1	J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035
1	J:174604 Sudarov A, Turnbull RK, Kim EJ, Lebel-Potter M, Guillemot F, Joyner AL, Ascl1 genetics reveals insights into cerebellum local circuit assembly. J Neurosci. 2011 Jul 27;31(30):11055-69
1	J:91404 Tokunaga A, Kohyama J, Yoshida T, Nakao K, Sawamoto K, Okano H, Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain. J Neurochem. 2004 Jul;90(1):142-54
1	J:150808 Tuoc TC, Radyushkin K, Tonchev AB, Pinon MC, Ashery-Padan R, Molnar Z, Davidoff MS, Stoykova A, Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice. J Neurosci. 2009 Jul 1;29(26):8335-49
1	J:317436 Turrero Garcia M, Stegmann SK, Lacey TE, Reid CM, Hrvatin S, Weinreb C, Adam MA, Nagy MA, Harwell CC, Transcriptional profiling of sequentially generated septal neuron fates. Elife. 2021 Dec 1;10:e71545
1	J:127418 Uemura M, Nakao S, Suzuki ST, Takeichi M, Hirano S, OL-Protocadherin is essential for growth of striatal axons and thalamocortical projections. Nat Neurosci. 2007 Sep;10(9):1151-9
1	J:217501 Vue TY, Kim EJ, Parras CM, Guillemot F, Johnson JE, Ascl1 controls the number and distribution of astrocytes and oligodendrocytes in the gray matter and white matter of the spinal cord. Development. 2014 Oct;141(19):3721-31
1	J:213986 Watatani K, Hirabayashi Y, Itoh Y, Gotoh Y, PDK1 regulates the generation of oligodendrocyte precursor cells at an early stage of mouse telencephalic development. Genes Cells. 2012 Apr;17(4):326-35
1	J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65
1	J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34
1	J:295961 Yabut OR, Ng HX, Yoon K, Arela JC, Ngo T, Pleasure SJ, The Neocortical Progenitor Specification Program Is Established through Combined Modulation of SHH and FGF Signaling. J Neurosci. 2020 Sep 2;40(36):6872-6887